Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis.

  title={Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis.},
  author={B. Bader‐Meunier and F. Gauthier and F. Archambaud and T. Cynober and F. Mi{\'e}lot and J. Dommergues and J. Warszawski and N. Mohandas and G. Tchernia},
  volume={97 2},
  • B. Bader‐Meunier, F. Gauthier, +6 authors G. Tchernia
  • Published 2001
  • Medicine
  • Blood
  • Clinical manifestations of hereditary spherocytosis (HS) can be abrogated by splenectomy. However, concerns exist regarding exposure of patients to a lifelong risk for overwhelming infections and, to a lesser extent, to vascular complications after total splenectomy. In the search for alternative treatment modalities, we assessed, in a previous pilot study, the potential usefulness of subtotal splenectomy in a small population of patients. During a mean follow-up period of 3.5 years, subtotal… CONTINUE READING
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