Long-term ethanol effects on acute stress responses: modulation by dynorphin.

  title={Long-term ethanol effects on acute stress responses: modulation by dynorphin.},
  author={Ildik{\'o} R{\'a}cz and Astrid Markert and Daniela Mauer and Birgit Stoffel-Wagner and Andreas Zimmer},
  journal={Addiction biology},
  volume={18 4},
The brain stress-response system is critically involved in the addiction process, stimulating drug consumption and the relapse to drug taking in abstinent addicts. At the same time, its functioning is affected by chronic drug exposure. Here, we have investigated the role of the endogenous opioid peptide dynorphin as a modulator of effects of long-term ethanol consumption on the brain stress-response system. Using the two-bottle choice paradigm, we demonstrate an enhanced ethanol preference in… CONTINUE READING


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The Authors, Addiction Biology © 2012 Society for the Study of Addiction

  • Ildikó Rácz
  • 2012

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