Long-term efficacy of spironolactone on pain, mood, and quality of life in women with fibromyalgia: An observational case series

  title={Long-term efficacy of spironolactone on pain, mood, and quality of life in women with fibromyalgia: An observational case series},
  author={H. Wernze and Thomas Herdegen},
  journal={Scandinavian Journal of Pain},
  pages={63 - 71}
Abstract Objective No single drug is broadly efficacious in the long-term treatment of fibromyalgia syndrome (FMS). Spironolactone is known to ameliorate mood and tension headache or migraine in women with premenstrual syndrome or clinical signs of hyperandrogenism. In a case series of women with treatment resistant FMS spironolactone was therefore added to their medication, and they were observed for at least 12 months. Methods 31 women with treatment-resistant FMS received spironolactone as… Expand
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