Long-term efficacy and tolerability of tacrolimus 0.03% ointment in infants:* a two-year open-label study.

@article{Mandelin2012LongtermEA,
  title={Long-term efficacy and tolerability of tacrolimus 0.03% ointment in infants:* a two-year open-label study.},
  author={Johanna M Mandelin and Andris Rubins and Anita Remitz and Kristine Cirule and James D. Dickinson and Vincent Ho and Mika Juhani M{\"a}kel{\"a} and Silvestrs Rubins and Sakari Reitamo and Nasrullah Undre},
  journal={International journal of dermatology},
  year={2012},
  volume={51 1},
  pages={104-10}
}
BACKGROUND Tacrolimus ointment is effective for treatment of moderate to severe atopic dermatitis (AD) in children aged ≥2 years (Br J Dermatol, 2004; 150: 554). Here, efficacy and tolerability of tacrolimus 0.03% ointment were evaluated in 50 infants aged <2 years at start of treatment. METHODS Infants with AD previously enrolled in a tacrolimus ointment pharmacokinetics trial were eligible for a 24-month open-label phase II study. Tacrolimus 0.03% ointment was applied to affected areas… CONTINUE READING
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