Long-term efficacy and safety comparison of sertindole and haloperidol in the treatment of schizophrenia. The Sertindole Study Group.

@article{Daniel1998LongtermEA,
  title={Long-term efficacy and safety comparison of sertindole and haloperidol in the treatment of schizophrenia. The Sertindole Study Group.},
  author={David Gordon Daniel and Patricia Wozniak and R. J. Mack and B G McCarthy},
  journal={Psychopharmacology bulletin},
  year={1998},
  volume={34 1},
  pages={61-9}
}
Sertindole is an atypical antipsychotic that is efficacious in schizophrenia and is associated infrequently with extrapyramidal symptoms (EPS). This study assessed time to treatment failure with 24 mg/day sertindole or 10 mg/day haloperidol in 282 clinically stable neuroleptic-responsive outpatients with schizophrenia. During a 5-week transition period, patients were randomized to treatment with sertindole or haloperidol; other treatments were gradually discontinued. Patients then received… CONTINUE READING
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