Long-term effects of repeated autologous transplantation of bone marrow cells in patients affected by peripheral arterial disease

@article{Cobellis2008LongtermEO,
  title={Long-term effects of repeated autologous transplantation of bone marrow cells in patients affected by peripheral arterial disease},
  author={Gilda Cobellis and Andrea Silvestroni and Stefano Lillo and Gabriel Sica and Chiara Botti and Ciro Maione and Vincenzo Schiavone and S. Della Rocco and Giancarlo Brando and Vincenzo Sica},
  journal={Bone Marrow Transplantation},
  year={2008},
  volume={42},
  pages={667-672}
}
Long-term effects of autologous mononuclear bone marrow cell transplantation were studied in patients with severe peripheral arterial disease (PAD) and critical limb ischemia. Ten patients with end-stage disease were infused twice with autologous bone marrow cells and they completed the 12-month follow-up study. Substantial improvement of blood flow and increasing capillary densities were seen when compared with a concomitant control group comprising patients who did not enroll in the study… CONTINUE READING