Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data

@article{Shine2015LongtermEO,
  title={Long-term effects of lithium on renal, thyroid, and parathyroid function: a retrospective analysis of laboratory data},
  author={Brian S.F. Shine and Rebecca F. McKnight and Laurence Leaver and John R. Geddes},
  journal={The Lancet},
  year={2015},
  volume={386},
  pages={461-468}
}
BACKGROUND Lithium is a widely used and highly effective treatment for mood disorders, but causes poorly characterised adverse effects in kidney and endocrine systems. We aimed to analyse laboratory information system data to determine the incidence of renal, thyroid, and parathyroid dysfunction associated with lithium use. METHODS In a retrospective analysis of laboratory data from Oxford University Hospitals National Health Service Trust (Oxfordshire, UK), we investigated the incidence of… CONTINUE READING
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