Long-term effects of immunosuppressive therapy on lung function in scleroderma patients

@article{PavlovDolijanovic2018LongtermEO,
  title={Long-term effects of immunosuppressive therapy on lung function in scleroderma patients},
  author={Slavica Pavlov-Dolijanovic and Nada Vujasinovic Stupar and Vladimir Zugic and Predrag M Ostoji{\'c} and Ana Zekovic and Tatjana Zivanovic Radnic and Ivan R Jeremic and Ivana Tadic},
  journal={Clinical Rheumatology},
  year={2018},
  pages={1-8}
}
The study aims to analyze the effects of induction treatment with cyclophosphamide (CYC) pulse therapy followed by maintenance treatment with other mild immunosuppressive agents on lung function in scleroderma (SSc) patients. Thirty patients with SSc (mean age 52 years, mean disease duration < 2 years) with forced vital capacity (FVC) ≤ 80% and/or diffusing capacity of carbon monoxide (DLco) ≤ 70% were included. Monthly CYC pulses were given for 6 months (induction treatment), followed by 3… CONTINUE READING
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