Long-term effects of growth factors on pH and acid-base transport in rat glomerular mesangial cells.

@article{Ganz1994LongtermEO,
  title={Long-term effects of growth factors on pH and acid-base transport in rat glomerular mesangial cells.},
  author={Michael B. Ganz and Walter F. Boron},
  journal={The American journal of physiology},
  year={1994},
  volume={266 4 Pt 2},
  pages={F576-85}
}
We investigated the long-term effects of exposing mesangial cells (MCs), previously quiescent, to platelet-derived growth factor, arginine vasopressin (AVP), epidermal growth factor, and serotonin (5-HT). MCs were exposed to the mitogens continuously for periods of 30-70 h. For each agent, we periodically measured intracellular pH (pH(i)), activities of Na… CONTINUE READING