Long-term effects of fenofibrate on carotid intima-media thickness and augmentation index in subjects with type 2 diabetes mellitus.

@article{Hiukka2008LongtermEO,
  title={Long-term effects of fenofibrate on carotid intima-media thickness and augmentation index in subjects with type 2 diabetes mellitus.},
  author={Anne Hiukka and Jukka Westerbacka and Eeva S. Leinonen and Hiroshi Watanabe and Olov Wiklund and Lillemor Mattson Hult{\'e}n and Jukka Salonen and Tomi-Pekka Tuomainen and Hannele Yki-J{\"a}rvinen and Anthony C Keech and Marja-Riitta Taskinen},
  journal={Journal of the American College of Cardiology},
  year={2008},
  volume={52 25},
  pages={2190-7}
}
OBJECTIVES The aim of this substudy was to ascertain whether long-term treatment with fenofibrate reduces surrogate measures of atherosclerosis, biomarkers of inflammation, and endothelial activation in patients with type 2 diabetes. BACKGROUND Some fibrates may decrease cardiovascular events, improve endothelial function, and reduce levels of acute-phase proteins. In the FIELD (Fenofibrate Intervention and Event Lowering in Diabetes) study, fenofibrate failed to decrease the primary end… CONTINUE READING