Long-term effects of caffeine therapy for apnea of prematurity.

@article{Schmidt2007LongtermEO,
  title={Long-term effects of caffeine therapy for apnea of prematurity.},
  author={B. Schmidt and R. Roberts and P. Davis and L. Doyle and K. Barrington and A. Ohlsson and A. Solimano and W. Tin},
  journal={The New England journal of medicine},
  year={2007},
  volume={357 19},
  pages={
          1893-902
        }
}
  • B. Schmidt, R. Roberts, +5 authors W. Tin
  • Published 2007
  • Medicine
  • The New England journal of medicine
  • BACKGROUND Methylxanthine therapy is commonly used for apnea of prematurity but in the absence of adequate data on its efficacy and safety. It is uncertain whether methylxanthines have long-term effects on neurodevelopment and growth. METHODS We randomly assigned 2006 infants with birth weights of 500 to 1250 g to receive either caffeine or placebo until therapy for apnea of prematurity was no longer needed. The primary outcome was a composite of death, cerebral palsy, cognitive delay… CONTINUE READING

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    This is a clinical trial which will investigate whether administration of caffeine, a respiratory stimulant, to preterm babies soon after birth can prevent the need for a breathing… Expand
    ConditionsApnea of Prematurity, BPD - Bronchopulmonary Dysplasia, Hemodynamic Instability, (+1 more)
    InterventionDrug
    INTERVENTIONAL CLINICAL TRIAL
    In premature infants, apnea of prematurity is one of their major clinical problems. Caffeine is currently a worldwide therapy to reduce the number and severity of these apneas. This… Expand
    ConditionsApnea of Prematurity
    InterventionOther
    INTERVENTIONAL CLINICAL TRIAL
    Apnea of prematurity is a common condition that is usually treated with methylxanthines. Methylxanthines are adenosine receptor blockers that have powerful influences on the central… Expand
    ConditionsApnea of Prematurity
    InterventionDrug
    Timing of caffeine therapy in very low birth weight infants.
    19
    Caffeine: an evidence-based success story in VLBW pharmacotherapy
    9

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