Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age.

@article{Marcus2014LongtermEO,
  title={Long-term effects of caffeine therapy for apnea of prematurity on sleep at school age.},
  author={Carole L. Marcus and Lisa J. Meltzer and R. S. Roberts and Joel T Traylor and Joanne Dix and Judy D'ilario and Elizabeth V Asztalos and Gillian F Opie and Lex W. Doyle and Sarah N. Biggs and Gillian M. Nixon and Indra Narang and Rakesh Bhattacharjee and Margot J. Davey and Rosemary S C Horne and Maureen Cheshire and Jeremy Gibbons and Lorrie Costantini and Ruth M Bradford and Barbara Schmidt},
  journal={American journal of respiratory and critical care medicine},
  year={2014},
  volume={190 7},
  pages={791-9}
}
RATIONALE Apnea of prematurity is a common condition that is usually treated with caffeine, an adenosine receptor blocker that has powerful influences on the central nervous system. However, little is known about the long-term effects of caffeine on sleep in the developing brain. OBJECTIVES We hypothesized that neonatal caffeine use resulted in long-term abnormalities in sleep architecture and breathing during sleep. METHODS A total of 201 ex-preterm children aged 5-12 years who… CONTINUE READING
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Longterm effects of caffeine therapy for apnea of prematurity on sleep

  • CL Marcus, LJ Meltzer, RS Roberts
  • Sleep 37,
  • 2014

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