Long term effects of Toki-shakuyaku-san on brain dopamine and nerve growth factor in olfactory-bulb-lesioned mice.

@article{Song2001LongTE,
  title={Long term effects of Toki-shakuyaku-san on brain dopamine and nerve growth factor in olfactory-bulb-lesioned mice.},
  author={Q. H. Song and Kazuo Toriizuka and Guang Bi Jin and Takeshi Yabe and Jong Chol Cyong},
  journal={Japanese journal of pharmacology},
  year={2001},
  volume={86 2},
  pages={183-8}
}
We used olfactory-bulb-lesioned mice induced by intranasal irrigation with zinc sulfate as a model of dementia, to investigate the effects of Toki-shakuyaku-san (TSS) on monoamines and nerve growth factor (NGF) in brain regions. TSS was given daily through the drinking water for either 1, 2, 3, 4 or 8 weeks from the day after olfactory lesion. The… CONTINUE READING