Long-term effects of "ecstasy" use on serotonin transporters of the brain investigated by PET.

@article{Buchert2003LongtermEO,
  title={Long-term effects of "ecstasy" use on serotonin transporters of the brain investigated by PET.},
  author={Ralph Buchert and Rainer Thomasius and Bruno Nebeling and Kay Petersen and Jost Obrocki and Lars Jenicke and Florian Wilke and Lutz Wartberg and Pavlina Zapletalova and Malte Clausen},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={2003},
  volume={44 3},
  pages={375-84}
}
UNLABELLED Alterations of the serotonergic system due to ecstasy consumption have been extensively documented in recent literature. However, reversibility of these neurotoxic effects still remains unclear. To address this question, PET was performed using the serotonin transporter (SERT) ligand (11)C-(+)-McN5652 in a total of 117 subjects subdivided into 4 groups: actual ecstasy users (n = 30), former ecstasy users (n = 29), drug-naive control subjects (n = 29), and subjects with abuse of… CONTINUE READING