Long-term effect of gonadotropin-releasing hormone agonist therapy on final and near-final height in 26 children with true precocious puberty treated at a median age of less than 5 years.

@article{Paul1995LongtermEO,
  title={Long-term effect of gonadotropin-releasing hormone agonist therapy on final and near-final height in 26 children with true precocious puberty treated at a median age of less than 5 years.},
  author={Dilip Paul and Felix A Conte and Melvin M. Grumbach and Selna L Kaplan},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1995},
  volume={80 2},
  pages={546-51}
}
We report a long term study on the effectiveness of chronic GnRH agonist treatment on final or near-final height in 26 patients (20 females and six males) with true precocious puberty (TPP). This study differs from other treatment studies in that the median age at onset of therapy was 4.7 yr for females and 6.2 yr for males, the youngest cohort of treated patients reported to date. We compared patients treated with GnRH agonists who attained final or near-final height with a historical control… CONTINUE READING
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