Long-term donor-specific tolerance in rat cardiac allografts by intrabone marrow injection of donor bone marrow cells.


BACKGROUND Donor-specific central tolerance in cardiac allograft can be induced by hematopoietic chimerism via conventional intravenous bone marrow transplantation (IV-BMT). However, there are problems with IV-BMT, such as the risk of graft failure and of the toxicity from conditioning regimens. METHODS A new method for heart transplantation is presented… (More)
DOI: 10.1097/01.tp.0000296061.71662.76