Long-term depression of neuron to glial signalling in rat cerebellar cortex.

@article{Bellamy2006LongtermDO,
  title={Long-term depression of neuron to glial signalling in rat cerebellar cortex.},
  author={Tomas C. Bellamy and David Ogden},
  journal={The European journal of neuroscience},
  year={2006},
  volume={23 2},
  pages={581-6}
}
Bergmann glial cells enclose synapses throughout the molecular layer of the cerebellum and express extrasynaptic AMPA receptors and glutamate transporters. Accordingly, stimulation of parallel fibres leads to the generation of inward currents in the glia due to AMPA receptor activation and electrogenic uptake of glutamate. Elimination of AMPA receptor Ca(2+) permeability leads to the withdrawal of glial processes and synaptic dysfunction, suggesting that AMPA receptor-mediated Ca(2+) signalling… CONTINUE READING