Long-term depression of C-fibre-evoked spinal field potentials by stimulation of primary afferent A delta-fibres in the adult rat.

@article{Liu1998LongtermDO,
  title={Long-term depression of C-fibre-evoked spinal field potentials by stimulation of primary afferent A delta-fibres in the adult rat.},
  author={Xiuxin Liu and Cecil R Morton and Jon Jatsu Azkue and Manfred Zimmermann and J{\"u}rgen Sandk{\"u}hler},
  journal={The European journal of neuroscience},
  year={1998},
  volume={10 10},
  pages={3069-75}
}
Long-term potentiation (LTP) of spinal C-fibre-evoked field potentials can be induced by brief electrical stimulation of afferent C-fibres, by natural noxious stimulation of skin or by acute nerve injury. Here, we report that in urethane anaesthetized, adult rats prolonged high frequency burst stimulation of the sciatic nerve at Adelta-fibre strength produced long-term depression (LTD) of C-fibre-evoked field potentials, and also depressed the increased amplitudes of C-fibre-evoked field… CONTINUE READING
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