Long-term depression at the mossy fiber-deep cerebellar nucleus synapse.

  title={Long-term depression at the mossy fiber-deep cerebellar nucleus synapse.},
  author={Wei Zhang and David E. J. Linden},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={26 26},
Several lines of evidence have indicated that the deep cerebellar nuclei (DCN) are a site of memory storage for certain forms of motor learning, most notably associative eyelid conditioning. In particular, these experiments, together with network models, have implicated the excitatory glutamatergic synapse between mossy fibers and DCN neurons in this memory trace. However, to date, evidence for persistent use-dependent change in the strength of this synapse has been almost entirely absent. Here… CONTINUE READING


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