Long-term cortical CBF recording by laser-Doppler flowmetry in awake freely moving rats subjected to reversible photothrombotic stroke.

@article{Gu1999LongtermCC,
  title={Long-term cortical CBF recording by laser-Doppler flowmetry in awake freely moving rats subjected to reversible photothrombotic stroke.},
  author={Weigang Gu and Wei Jiang and Thomas Br{\"a}nnstr{\"o}m and Per Wester},
  journal={Journal of neuroscience methods},
  year={1999},
  volume={90 1},
  pages={23-32}
}
This study aimed at developing a laser-Doppler flowmetry (LDF) device suitable for long-term cortical cerebral blood flow (cCBF) measurement in awake, freely moving rats. The device included a flow probe adapter for permanent fixation to the skull bone and a connector that held the flow probe in the adapter in exactly the same position during repeated cCBF recordings. With this LDF recording system, cCBF values were stable and unaltered in awake, freely moving rats up to 4 days after operation… CONTINUE READING
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