Long-term consumption of aspartame and brain antioxidant defense status

@article{Abhilash2013LongtermCO,
  title={Long-term consumption of aspartame and brain antioxidant defense status},
  author={M. Abhilash and M. V. Sauganth Paul and Mathews Valuparampil Varghese and Raveendran Harikumaran Nair},
  journal={Drug and Chemical Toxicology},
  year={2013},
  volume={36},
  pages={135 - 140}
}
  • M. Abhilash, M.V. Sauganth Paul, +1 author Raveendran Harikumaran Nair
  • Published 2013
  • Medicine, Chemistry
  • Drug and Chemical Toxicology
  • The present study investigated the effect of long-term intake of aspartame, a widely used artificial sweetener, on antioxidant defense status in the rat brain. Male Wistar rats weighing 150–175 g were randomly divided into three groups as follows: The first group was given aspartame at a dose of 500 mg/kg body weight (b.w.); the second group was given aspartame at dose of 1,000 mg/kg b.w., respectively, in a total volume of 3 mL of water; and the control rats received 3 mL of distilled water… CONTINUE READING

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