Long-term consequences for offspring of diabetes during pregnancy.

  title={Long-term consequences for offspring of diabetes during pregnancy.},
  author={Frans Andr{\'e} Van Assche and Kathleen Holemans and Leona Aerts},
  journal={British medical bulletin},
There is evidence that the diabetic intra-uterine environment has consequences for later life. Maternal diabetes mainly results in asymmetric macrosomia. This macrosomia is associated with an increased insulin secretion and overstimulation of the insulin producing B-cells during fetal life. In later life, a reduced insulin secretion is found. Intra-uterine growth restriction is present in severe maternal diabetes associated with vasculopathy. Intra-uterine growth restriction is associated with… CONTINUE READING
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