Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen

@article{Nielsen1995LongtermCO,
  title={Long-term comparison of human insulin analogue B10Asp and soluble human insulin in IDDM patients on a basal/bolus insulin regimen},
  author={Dr. F. S. Nielsen and Lars Nannestad J\orgensen and Merete Ipsen and A. I. Voldsgaard and H. -H. Parving},
  journal={Diabetologia},
  year={1995},
  volume={38},
  pages={592-598}
}
Recombinant DNA technology allows the production of insulin analogues with faster absorption rates from subcutaneous tissue as compared to soluble human insulin. The human insulin analogue B10Asp (mono/dimeric) is absorbed twice as fast as soluble human insulin (hexameric). A double blind, randomised crossover study with a 1-month run-in period and two 2-month treatment periods was performed in 21 male insulin-dependent diabetic (IDDM) patients aged 18–40 years in order to compare the metabolic… CONTINUE READING

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