Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.

  title={Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.},
  author={Frank A. Lederle and J. Freischlag and Tassos C Kyriakides and Jon S. Matsumura and Frank T. Padberg and Ted R. Kohler and Panagiotis Kougias and Jessie M. Jean-Claude and Dolores F. Cikrit and Kathleen M. Swanson},
  journal={The New England journal of medicine},
  volume={367 21},
BACKGROUND Whether elective endovascular repair of abdominal aortic aneurysm reduces long-term morbidity and mortality, as compared with traditional open repair, remains uncertain. METHODS We randomly assigned 881 patients with asymptomatic abdominal aortic aneurysms who were candidates for both procedures to either endovascular repair (444) or open repair (437) and followed them for up to 9 years (mean, 5.2). Patients were selected from 42 Veterans Affairs medical centers and were 49 years… Expand

Paper Mentions

Interventional Clinical Trial
Abdominal aortic aneurysms (AAAs) continue to be a leading cause of death in older age groups. In the 60-85 year-old population, AAA represents the 14th-leading cause of death… Expand
ConditionsAbdominal Aortic Aneurysm
Open versus Endovascular Repair of Abdominal Aortic Aneurysm.
The results were not consistent with the findings of worse performance of endovascular repair with respect to long-term survival that was seen in the two European trials, and the number of patients who underwent secondary therapeutic procedures was noted. Expand
Long-Term Outcomes of Abdominal Aortic Aneurysm in the Medicare Population.
Endovascular repair, as compared with open repair, of abdominal aortic aneurysm was associated with a substantial early survival advantage that gradually decreased over time and the rate of late rupture was significantly higher after endov vascular repair than after open repair. Expand
Durability and survival are similar after elective endovascular and open repair of abdominal aortic aneurysms in younger patients.
After elective aneurysm repair, younger patients have a moderate life expectancy related to malignant disease and cardiovascular health and EVAR offers durability and long-term survival similar to those with open repair in these younger patients as long as aneurYSm anatomy and IFU are adhered to. Expand
Long-term Outcomes Following Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysms
Emergency EVAR for ruptured AAA can be performed with acceptable short-term outcomes; however, long-term surveillance is necessary, and reintervention is common. Expand
Endovascular vs Open Aneurysm Repair in the Young
Purpose: To examine the results of elective abdominal aortic aneurysm (AAA) repair in young patients (<70 years old) and compare the outcome of endovascular aneurysm repair (EVAR) and open surgicalExpand
Endovascular Versus Open Repair of Intact Descending Thoracic Aortic Aneurysms.
TEVAR should be considered the first line for repair of intact descending thoracic aortic aneurysms in Medicare beneficiaries after open surgical repair, and mean survival was superior for TEVAR. Expand
Rate of Secondary Intervention After Open Versus Endovascular Abdominal Aortic Aneurysm Repair.
Patients treated with EVAR had a significantly lower overall rate of secondary intervention compared with patients treated with open AAA repair, likely secondary to increased perioperative morbidity and mortality and a bias toward more complex patients in the open repair group. Expand
Long-term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysms: Retrospective Analysis of Matched Cohorts with Propensity Score.
Risk-adjusted comparisons revealed that long-term outcomes of ER and OS were comparable among relatively frail patients in their age 70s, and failed to show the long- term advantage of EVAR in rather high-risk patients and provided no supportive evidence for the selection criteria. Expand
Long‐term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms
There was no survival difference between patients who underwent open or endov vascular abdominal aortic aneurysm repair, despite a continuously increasing number of reinterventions in the endovascular repair group during 12 years of follow‐up. Expand
Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
The (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes. Expand


Two-year outcomes after conventional or endovascular repair of abdominal aortic aneurysms
The perioperative survival advantage with endovascular repair as compared with open repair is not sustained after the first postoperative year, with no significant difference in subsequent aneurysm-related mortality. Expand
Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial.
Perioperative mortality was low for both procedures and lower for endovascular than open repair in this report of short-term outcomes after elective AAA repair, and the early advantage of endov vascular repair was not offset by increased morbidity or mortality in the first 2 years after repair. Expand
The impact of gender on presentation, therapy, and mortality of abdominal aortic aneurysm in the United States, 2001-2004.
A gender difference in the outcomes following repair of abdominal aortic aneurysm has persisted over time, the cause of which is not explained by these or previous data, and warrants further investigation. Expand
Variation in hospital mortality associated with inpatient surgery.
Reducing mortality associated with inpatient surgery will require greater attention to the timely recognition and management of complications once they occur, and differences in rates of death among patients with major complications were also the primary determinant of variation in overall mortality with individual operations. Expand
Patient fitness and survival after abdominal aortic aneurysm repair in patients from the UK EVAR trials
  • L. Brown
  • Medicine
  • The British journal of surgery
  • 2007
The aim was to use a validated fitness score to determine whether fitter patients with a large abdominal aortic aneurysm (AAA) benefited from having open rather than endovascular repair.
Using Standardized Serum Creatinine Values in the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate
The MDRD Study equation has now been reexpressed for use with a standardized serum creatinine assay, allowing GFR estimates to be reported in clinical practice by using standardized serumcreatinine and overcoming this limitation to the current use of GFR estimating equations. Expand
Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction
For 1152 men (1036 with ED, 116 controls) analyzed, a receiver operating characteristic curve indicated that the IIEF-5 is an excellent diagnostic test. Expand
Accounting for Deaths in Longitudinal Studies Using the SF-36: The Performance of the Physical Component Scale of the Short Form 36-Item Health Survey and the PCTD
The Physical Component Transformed, with Deaths included (PCTD), which is the probability of being healthy 1 year later and for which deaths logically have a value of zero, is recommended for longitudinal analyses of physical health when deaths occur. Expand
US Valuation of the EQ-5D Health States: Development and Testing of the D1 Valuation Model
The D1 model best predicts the values for observed health states using the time trade-off method, and represents a significant enhancement of the EQ-5D's utility for health status assessment and economic analysis in the US. Expand
The Statistical Analysis of Failure Time Data
Preface.1. Introduction.1.1 Failure Time Data.1.2 Failure Time Distributions.1.3 Time Origins, Censoring, and Truncation.1.4 Estimation of the Survivor Function.1.5 Comparison of Survival Curves.1.6Expand