Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.

@article{Lederle2012LongtermCO,
  title={Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.},
  author={Frank A. Lederle and J. Freischlag and Tassos C Kyriakides and Jon S. Matsumura and Frank T. Padberg and Ted R. Kohler and Panagiotis Kougias and Jessie M. Jean-Claude and Dolores F. Cikrit and Kathleen M. Swanson},
  journal={The New England journal of medicine},
  year={2012},
  volume={367 21},
  pages={
          1988-97
        }
}
BACKGROUND Whether elective endovascular repair of abdominal aortic aneurysm reduces long-term morbidity and mortality, as compared with traditional open repair, remains uncertain. METHODS We randomly assigned 881 patients with asymptomatic abdominal aortic aneurysms who were candidates for both procedures to either endovascular repair (444) or open repair (437) and followed them for up to 9 years (mean, 5.2). Patients were selected from 42 Veterans Affairs medical centers and were 49 years… Expand

Paper Mentions

Interventional Clinical Trial
Abdominal aortic aneurysms (AAAs) continue to be a leading cause of death in older age groups. In the 60-85 year-old population, AAA represents the 14th-leading cause of death… Expand
ConditionsAbdominal Aortic Aneurysm
InterventionProcedure
Open versus Endovascular Repair of Abdominal Aortic Aneurysm.
TLDR
The results were not consistent with the findings of worse performance of endovascular repair with respect to long-term survival that was seen in the two European trials, and the number of patients who underwent secondary therapeutic procedures was noted. Expand
Long-Term Outcomes of Abdominal Aortic Aneurysm in the Medicare Population.
TLDR
Endovascular repair, as compared with open repair, of abdominal aortic aneurysm was associated with a substantial early survival advantage that gradually decreased over time and the rate of late rupture was significantly higher after endov vascular repair than after open repair. Expand
Durability and survival are similar after elective endovascular and open repair of abdominal aortic aneurysms in younger patients.
TLDR
After elective aneurysm repair, younger patients have a moderate life expectancy related to malignant disease and cardiovascular health and EVAR offers durability and long-term survival similar to those with open repair in these younger patients as long as aneurYSm anatomy and IFU are adhered to. Expand
Long-term Outcomes Following Endovascular Aneurysm Repair for Ruptured Abdominal Aortic Aneurysms
TLDR
Emergency EVAR for ruptured AAA can be performed with acceptable short-term outcomes; however, long-term surveillance is necessary, and reintervention is common. Expand
Endovascular vs Open Aneurysm Repair in the Young
Purpose: To examine the results of elective abdominal aortic aneurysm (AAA) repair in young patients (<70 years old) and compare the outcome of endovascular aneurysm repair (EVAR) and open surgicalExpand
Endovascular Versus Open Repair of Intact Descending Thoracic Aortic Aneurysms.
TLDR
TEVAR should be considered the first line for repair of intact descending thoracic aortic aneurysms in Medicare beneficiaries after open surgical repair, and mean survival was superior for TEVAR. Expand
Rate of Secondary Intervention After Open Versus Endovascular Abdominal Aortic Aneurysm Repair.
TLDR
Patients treated with EVAR had a significantly lower overall rate of secondary intervention compared with patients treated with open AAA repair, likely secondary to increased perioperative morbidity and mortality and a bias toward more complex patients in the open repair group. Expand
Long-term Comparison of Endovascular and Open Repair of Abdominal Aortic Aneurysms: Retrospective Analysis of Matched Cohorts with Propensity Score.
TLDR
Risk-adjusted comparisons revealed that long-term outcomes of ER and OS were comparable among relatively frail patients in their age 70s, and failed to show the long- term advantage of EVAR in rather high-risk patients and provided no supportive evidence for the selection criteria. Expand
Long‐term survival and secondary procedures after open or endovascular repair of abdominal aortic aneurysms
TLDR
There was no survival difference between patients who underwent open or endov vascular abdominal aortic aneurysm repair, despite a continuously increasing number of reinterventions in the endovascular repair group during 12 years of follow‐up. Expand
Abdominal Aortic Aneurysm Repair: Results from a Series of Young Patients
TLDR
The (albeit limited) experience suggests that, in an unselected young patient population undergoing elective AAA repair, OR or EVAR can be performed safely with similar immediate and long term outcomes. Expand
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