Long-term comparison between captopril and nifedipine in the progression of renal insufficiency.

@article{Zucchelli1992LongtermCB,
  title={Long-term comparison between captopril and nifedipine in the progression of renal insufficiency.},
  author={Pietro C Zucchelli and Alessandro Zuccal{\`a} and Martina Borghi and Maurizio Fusaroli and Massimo Sasdelli and Carmine Stallone and Giovanna Maria Sanna and Rossella Gaggi},
  journal={Kidney international},
  year={1992},
  volume={42 2},
  pages={
          452-8
        }
}
To verify the hypothesis that angiotensin-converting enzyme (ACE) inhibitors possess a unique renoprotective effect in progressive chronic renal disease, we decided to compare the effects of an ACE inhibitor and a calcium antagonist on both hypertension and the progression of non-diabetic renal insufficiency in a long-term study. A four-year, multicenter, prospective, randomized trial was conducted on 142 hypertensive patients (pts) with established chronic renal failure from six Italian… CONTINUE READING
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