Long-term clinical efficacy of grass-pollen immunotherapy.

@article{Durham1999LongtermCE,
  title={Long-term clinical efficacy of grass-pollen immunotherapy.},
  author={Stephen R. Durham and Samantha M. Walker and Eva M Varga and Mikila R Jacobson and F O'brien and W Noble and Stephen J Till and Qutayba Hamid and Kayhan T. Nouri-Aria},
  journal={The New England journal of medicine},
  year={1999},
  volume={341 7},
  pages={
          468-75
        }
}
BACKGROUND Pollen immunotherapy is effective in selected patients with IgE-mediated seasonal allergic rhinitis, although it is questionable whether there is long-term benefit after the discontinuation of treatment. METHODS We conducted a randomized, double-blind, placebo-controlled trial of the discontinuation of immunotherapy for grass-pollen allergy in patients in whom three to four years of this treatment had previously been shown to be effective. During the three years of this trial… 
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TLDR
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