Long-term clinical efficacy of grass-pollen immunotherapy.
@article{Durham1999LongtermCE, title={Long-term clinical efficacy of grass-pollen immunotherapy.}, author={S. Durham and S. Walker and E. Varga and M. Jacobson and F. O'Brien and W. Noble and S. Till and Q. Hamid and K. Nouri-Aria}, journal={The New England journal of medicine}, year={1999}, volume={341 7}, pages={ 468-75 } }
BACKGROUND
Pollen immunotherapy is effective in selected patients with IgE-mediated seasonal allergic rhinitis, although it is questionable whether there is long-term benefit after the discontinuation of treatment.
METHODS
We conducted a randomized, double-blind, placebo-controlled trial of the discontinuation of immunotherapy for grass-pollen allergy in patients in whom three to four years of this treatment had previously been shown to be effective. During the three years of this trial… CONTINUE READING
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