Long-term circulation of vaccine-derived poliovirus that causes paralytic disease.

@article{Cherkasova2002LongtermCO,
  title={Long-term circulation of vaccine-derived poliovirus that causes paralytic disease.},
  author={Elena A. Cherkasova and Ekaterina A Korotkova and Maria L Yakovenko and Olga E. Ivanova and Tatyana P Eremeeva and Konstantin Chumakov and Vadim I Agol},
  journal={Journal of virology},
  year={2002},
  volume={76 13},
  pages={
          6791-9
        }
}
Successful implementation of the global poliomyelitis eradication program raises the problem of vaccination against poliomyelitis in the posteradication era. One of the options under consideration envisions completely stopping worldwide the use of the Sabin vaccine. This strategy is based on the assumption that the natural circulation of attenuated strains and their derivatives is strictly limited. Here, we report the characterization of a highly evolved derivative of the Sabin vaccine strain… CONTINUE READING

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