Long-term chronic recording from cortical neurons

  title={Long-term chronic recording from cortical neurons},
  author={Edward M. Schmidt and Martin Bak and Jr. S. Mcintosh},
  journal={Experimental Neurology},
Recording from the same neurons chronically in motor cortex.
Two rhesus monkeys were implanted with silicon arrays of 96 microelectrodes and performed a center-out reaching task, and it was found that the firing properties of chronically recorded neurons were stable over time.
An economical multi-channel cortical electrode array for extended periods of recording during behavior
A low-cost chronic multi-channel microwire electrode array for recording multi-unit cortical responses in behaving rodents and the design was motivated by three issues.


Design, fabrication, and in vivo behavior of chronic recording intracortical microelectrodes.
A platinum-glass microelectrode has been developed that permits chronic recording from single cortical neurons in unrestrained animals and without benefit of external manipulation. Details of
An instrument for separation of multiple-unit neuroelectric signals.
  • E. Schmidt
  • Engineering
    IEEE transactions on bio-medical engineering
  • 1971
An instrument for real-time separation of interleaved neuronal spike trains has been developed. Amplitude of the spike at two selectable time points provides the criteria for separating spikes into
Parylene as a Chronically Stable, Reproducible Microelectrode Insulator
The electric arc process used to expose Parylene-covered iridium and tungsten microelectrodes is found to give cleaner recording surfaces with impedances lower than those obtainable with previously described methods.
Recording for several days from single cortical neurons in completely unrestrained cats.
Glass Insulated Platinum Microelectrode
Microelectrodes for electrophysiological use have been prepared easily and quickly by electrolytically sharpening platinum iridium alloy wire and coating with molten glass. The desirable combination