Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor.

@article{Deak1999LongtermCI,
  title={Long-term changes in mineralocorticoid and glucocorticoid receptor occupancy following exposure to an acute stressor.},
  author={Terrence Deak and Kien T. Nguyen and Crystal S Cotter and Monika Fleshner and Linda R. Watkins and Steven F. Maier and Robert L Spencer},
  journal={Brain research},
  year={1999},
  volume={847 2},
  pages={211-20}
}
Stressors produce rapid activation of the hypothalamic-pituitary-adrenal axis, which typically resolves within 60-90 min following termination of the stressor. In addition, some stressors such as inescapable tailshock (IS) also produce elevated basal levels of corticosterone (CORT), and reduced serum levels of corticosteroid binding globulin (CBG). The elevated basal levels of CORT produced by IS are only observed at the trough of the circadian rhythm of CORT secretion, and are sustained for 2… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

A users guide to HPA axis research.

Physiology & behavior • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 37 references

The impact of the nonpeptide Corticotropin - Releasing Hormone antagonist Antalarmin on behavioral and endocrine responses to stress

P. Burbach, G. H. Mulder
Ž . Endocrinology • 1999

Regulation of hippocampal glucocorticoid receptor gene transcription and protein expression in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1998

The long term acute phaselike responses that follow acute stressor exposure are blocked by alphamelanocyte stimulating horŽ . mone

B. H. Natelson J. E. Ottenweller, D. L. Pitman, S. D. Drastal
Brain Research • 1998

Evidence that brief stress may induce the acute phase response in rats.

American journal of physiology. Regulatory, integrative and comparative physiology • 1997

A long - term increase in basal levels of corticosterone and a decrease in corticosteroidbinding globulin following Ž . acute stressor exposure

J. P. Herman
Endocrinology • 1995

The effect of acute and chronic ACTH administration on pituitary adrenal response to acute immobilization stress

M. Giralt A. Armario, O. Marti, +3 authors R. W. Kuhn
1994

Similar Papers

Loading similar papers…