Long-term cardiac toxicity after adjuvant epirubicin-based chemotherapy in early breast cancer: French Adjuvant Study Group results.

@article{Fumoleau2006LongtermCT,
  title={Long-term cardiac toxicity after adjuvant epirubicin-based chemotherapy in early breast cancer: French Adjuvant Study Group results.},
  author={Pierre Fumoleau and Henry Roch{\'e} and Pierre Kerbrat and Jacques Bonneterre and Pascale Romestaing and Pierre Fargeot and Mo{\"i}se Namer and Alain M Monnier and Philippe Montcuquet and M-J Goudier and Elisabeth Luporsi},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2006},
  volume={17 1},
  pages={85-92}
}
BACKGROUND The aim of the study was to evaluate and compare incidence and risk factors of left ventricular dysfunction (LVD) in early breast cancer patients receiving (E+) or not (E-) epirubicin-based adjuvant chemotherapy. PATIENTS AND METHODS Among eight FASG trials, 3577 assessable patients were analyzed retrospectively: 2553 received epirubicin, 662 received hormonotherapy alone and 362 had no systemic treatment. Chemotherapy was FEC regimen in 86% of cases (fluorouracil, epirubicin… CONTINUE READING
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