Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice.

@article{Cheng2014LongtermCT,
  title={Long-term cannabidiol treatment prevents the development of social recognition memory deficits in Alzheimer's disease transgenic mice.},
  author={David Xi Cheng and Adena S. Spiro and Andrew M. Jenner and Brett Garner and Tim Karl},
  journal={Journal of Alzheimer's disease : JAD},
  year={2014},
  volume={42 4},
  pages={1383-96}
}
Impairments in cognitive ability and widespread pathophysiological changes caused by neurotoxicity, neuroinflammation, oxidative damage, and altered cholesterol homeostasis are associated with Alzheimer's disease (AD). Cannabidiol (CBD) has been shown to reverse cognitive deficits of AD transgenic mice and to exert neuroprotective, anti-oxidative, and anti-inflammatory properties in vitro and in vivo. Here we evaluate the preventative properties of long-term CBD treatment in male AβPPSwe/PS1ΔE9… CONTINUE READING
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