Long-term calorie restriction decreases metabolic cost of movement and prevents decrease of physical activity during aging in rhesus monkeys

@article{Yamada2013LongtermCR,
  title={Long-term calorie restriction decreases metabolic cost of movement and prevents decrease of physical activity during aging in rhesus monkeys},
  author={Yosuke Yamada and Ricki J Colman and Joseph W. Kemnitz and Scott T. Baum and Rozalyn M Anderson and R. H. Weindruch and Dale A. Schoeller},
  journal={Experimental Gerontology},
  year={2013},
  volume={48},
  pages={1226-1235}
}
BACKGROUND Short-term (<1 year) calorie restriction (CR) has been reported to decrease physical activity and metabolic rate in humans and non-human primate models; however, studies examining the very long-term (>10 year) effect of CR on these parameters are lacking. OBJECTIVE The objective of this study was to examine metabolic and behavioral adaptations to long-term CR longitudinally in rhesus macaques. DESIGN Eighteen (10 male, 8 female) control (C) and 24 (14 male, 10 female) age matched… Expand
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