Long-term azithromycin use in patients with chronic obstructive pulmonary disease and tracheostomy.

@article{Blasi2010LongtermAU,
  title={Long-term azithromycin use in patients with chronic obstructive pulmonary disease and tracheostomy.},
  author={Francesco Blasi and Daniela R. Bonardi and Stefano Aliberti and Paolo Tarsia and Marco Confalonieri and Omar Amir and Mauro Carone and Fabiano Di Marco and Stefano Centanni and Enrico Eugenio Guffanti},
  journal={Pulmonary pharmacology & therapeutics},
  year={2010},
  volume={23 3},
  pages={200-7}
}
Patients with Chronic Obstructive Pulmonary Disease (COPD) and tracheostomy are at high risk for exacerbations and hospitalizations. Macrolide treatment has shown to reduce exacerbations in moderate-to-severe COPD. To evaluate the safety and the efficacy of long-term azithromycin use in outpatients with severe COPD and tracheostomy. A multicenter, randomized, uncontrolled, pilot trial evaluating the safety and the efficacy of azithromycin 500 mg three day-a-week for 6 months (AZI) vs. standard… CONTINUE READING

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