Long-term analysis of clinical outcome and complications in locally advanced cervical cancer patients administered concomitant chemoradiation followed by radical surgery.

@article{Ferrandina2010LongtermAO,
  title={Long-term analysis of clinical outcome and complications in locally advanced cervical cancer patients administered concomitant chemoradiation followed by radical surgery.},
  author={Gabriella Ferrandina and Pasquale Alessandro Margariti and Daniela Smaniotto and Marco Petrillo and Maria Giovanna Salerno and Anna Fagotti and Gabriella Macchia and Alessio Giuseppe Morganti and Numa Cellini and Giovanni Scambia},
  journal={Gynecologic oncology},
  year={2010},
  volume={119 3},
  pages={404-10}
}
OBJECTIVE Preoperative chemoradiation (CT/RT) has been shown to achieve encouraging results in terms of clinical outcome in locally advanced cervical cancer (LACC). The study aims at analyzing the long-term results of this multimodal approach in a single institution series of 184 cases. METHODS Patients underwent whole pelvic irradiation combined with cisplatin and 5-fluorouracil. After evaluation of clinical response, patients were triaged to surgery. Surgical morbidity was classified… CONTINUE READING

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