Long-term amitriptyline in chronic depression.


Medication was discontinued under a placebo-controlled, double-blind, six-month protocol with 17 chronically depressed patients who had been taking an average daily dose of 138 mg amitriptyline (AMI) for an average of 3.7 years. Only one of nine patients became depressed on active medication, while of the 15 patients receiving a placebo trial, 11 had a… (More)


Cite this paper

@article{Giller1985LongtermAI, title={Long-term amitriptyline in chronic depression.}, author={Earl Giller and D S Bialos and Laura M. Harkness and Peter I. Jatlow and Michael Waldo}, journal={The Hillside journal of clinical psychiatry}, year={1985}, volume={7 1}, pages={16-33} }