Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil.

@article{Quebbeman1985LongtermAT,
  title={Long-term ambulatory treatment of metastatic colorectal adenocarcinoma by continuous intravenous infusion of 5-fluorouracil.},
  author={Edward Quebbeman and Robert K. Ausman and Richard N Hansen and Th. Becker and Gonzalo Caballero and Paul S. Ritch and David Jenkins and Duncan Blake and L Tangen and W C Schulte},
  journal={Journal of surgical oncology},
  year={1985},
  volume={30 1},
  pages={60-5}
}
To delineate the efficacy of continuous intravenous 5-fluorouracil (5-FU) infusion therapy for advanced colorectal adenocarcinoma, a study of 36 patients with measurable metastatic disease was conducted. Patients received a daily intravenous infusion of 300 mg/m2 5-FU over a 24-h period utilizing portable infusion devices and central venous catheters. In a population characterized by substantial pretreatment exposure to radiotherapy, chemotherapy, and other indicators of poor prognosis, 13/36… CONTINUE READING

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