Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats

@article{Shi2008LongtermAO,
  title={Long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats},
  author={Z. Y. Shi and Ai-Dong Chen and Yao Xu and Qi Chen and Xing-ya Gao and Wei Wang and Guo-Qing Zhu},
  journal={Pfl{\"u}gers Archiv - European Journal of Physiology},
  year={2008},
  volume={458},
  pages={247-257}
}
The purpose of this study was to determine whether the long-term administration of tempol attenuates postinfarct ventricular dysfunction and sympathetic activity in rats. Myocardial infarction (MI) was induced by left descending coronary artery ligation. Tempol was orally administered in drinking water (2 mmol/L), which was initiated 4 h after infarction and continued for 6 weeks. Tempol prevented not only the increases in left ventricular end-diastolic pressure and volume but also the… CONTINUE READING
26 Citations
44 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Similar Papers

Loading similar papers…