Long-term adaptive changes induced by serotonergic antidepressant drugs.

Abstract

The development of conventional antidepressants has been largely based on the hypothesis of monoaminergic dysfunctions and focuses particularly on the serotonin 5-hydroxytryptamine (5-HT) system. Hence, various classes of antidepressant treatments enhance 5-HT neurotransmission with a time course consistent with their delayed therapeutic effect. This… (More)

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@article{Faure2006LongtermAC, title={Long-term adaptive changes induced by serotonergic antidepressant drugs.}, author={C{\'e}line Faure and Ouissame Mnie-Filali and Nasser Haddjeri}, journal={Expert review of neurotherapeutics}, year={2006}, volume={6 2}, pages={235-45} }