Long-term activation of protein kinase C by angiotensin II in cultured bovine adrenal medullary cells.

@article{Tuominen1991LongtermAO,
  title={Long-term activation of protein kinase C by angiotensin II in cultured bovine adrenal medullary cells.},
  author={Raimo K. Tuominen and Paul. hudson and M. McMillian and Honggang Ye and Michal K. Stachowiak and Jau Shong Hong},
  journal={Journal of neurochemistry},
  year={1991},
  volume={56 4},
  pages={1292-8}
}
Previous studies from our laboratory suggest that protein kinase C (PKC) is involved in the angiotensin II (AII)-induced increase in the expression of genes encoding proenkephalin and catecholamine biosynthesizing enzymes in primary cultured bovine adrenal medullary (BAM) cells. The purpose of this study was to examine the effects of [Sar1]-AII (S1-AII), an AII agonist, on PKC activity in BAM cells. Thirty-minute incubation with S1-AII produced a dose-dependent activation of PKC. The… CONTINUE READING