Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group.

@article{Flather2000LongtermAT,
  title={Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group.},
  author={Marcus D. Flather and Salim Yusuf and Lars Valeur K\ober and Marc Pfeffer and Alistair Scott Hall and Gordon Murray and Christian Torp-Pedersen and Stephen Ball and Janice Pogue and L. S. Moye and Eugene Braunwald},
  journal={Lancet},
  year={2000},
  volume={355 9215},
  pages={1575-81}
}
BACKGROUND We undertook a prospective systematic overview based on data from individual patients from five long-term randomised trials that assessed inhibitors of angiotensin-converting enzyme (ACE) in patients with left-ventricular dysfunction or heart failure. METHODS Three of the trials enrolled patients within a week after acute myocardial infarction. Data were combined by use of the Peto-Yusuf method. FINDINGS Overall 12,763 patients were randomly assigned treatment or placebo and… CONTINUE READING
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