Long-term (7-year) outcomes of universal mismatch repair screening (uMMR) of 1156 colorectal (CRC) and endometrial cancers (EC) in an academic setting.

@inproceedings{Hall2018LongtermO,
  title={Long-term (7-year) outcomes of universal mismatch repair screening (uMMR) of 1156 colorectal (CRC) and endometrial cancers (EC) in an academic setting.},
  author={Michael J Hall and Yana Chertock and Michelle Savage and Joann Sicilia and Mary B Daly},
  year={2018}
}
1513Background: uMMR of CRC/EC for Lynch syndrome (LS) is recommended to identify the 2-3% of incident CRC/EC with germline MMR mutations in MLH1, MSH2, MSH6, and PMS2. Many US centers use a positive immunohistochemical (IHC+) tumor test to prompt further evaluation such as genetic counseling (GC). Efficacy of uMMR is established, but real-world performance is not. W/recent Blue Ribbon Panel recommendations for broad implementation, we reviewed uMMR effectiveness in an academic cancer center… CONTINUE READING