Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.

@article{Ino2000LongSA,
  title={Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.},
  author={Yasushi Ino and Magdalena C. Zlatescu and Hikaru Sasaki and David W Macdonald and Anat Stemmer-Rachamimov and Sarah Jhung and David A. Ramsay and Andreas von Deimling and David N Louis and J. Gregory Cairncross},
  journal={Journal of neurosurgery},
  year={2000},
  volume={92 6},
  pages={983-90}
}
OBJECT Allelic loss of chromosome 1p is a powerful predictor of tumor chemosensitivity and prolonged survival in patients with anaplastic oligodendrogliomas. Chromosome 1p loss also occurs in astrocytic and oligoastrocytic gliomas, although less commonly than in pure oligodendroglial tumors. This observation raises the possibility investigated in this study… CONTINUE READING