Long range frontal/posterior phase synchronization during remembered pursuit task is impaired in schizophrenia

@article{Krishna2014LongRF,
  title={Long range frontal/posterior phase synchronization during remembered pursuit task is impaired in schizophrenia},
  author={Nithin Krishna and Hugh St C. O’Neill and Eva Mar{\'i}a S{\'a}nchez-Morla and Gunvant K. Thaker},
  journal={Schizophrenia Research},
  year={2014},
  volume={157},
  pages={198-203}
}
Although smooth pursuit eye movement (SPEM) is a reliable endophenotype of schizophrenia, exact underlying cognitive and neural substrates remain unknown. A simple mechanistic model of SPEM assumes an efficient interaction in integrating sensory input from the medial temporal (MT)/medial superior temporal (MST) brain regions and subsequent motor response through the frontal eye field (FEF). Poor functional connectivity between these two regions could explain impaired motion perception and SPEM… CONTINUE READING