Long-range correlations in nucleotide sequences

@article{Peng1992LongrangeCI,
  title={Long-range correlations in nucleotide sequences},
  author={C. Peng and S. Buldyrev and A. Goldberger and S. Havlin and F. Sciortino and M. Simons and H. Stanley},
  journal={Nature},
  year={1992},
  volume={356},
  pages={168-170}
}
  • C. Peng, S. Buldyrev, +4 authors H. Stanley
  • Published 1992
  • Biology, Medicine
  • Nature
  • DNA SEQUENCES have been analysed using models, such as an it-step Markov chain, that incorporate the possibility of short-range nucleotide correlations1. We propose here a method for studying the stochastic properties of nucleotide sequences by constructing a 1:1 map of the nucleotide sequence onto a walk, which we term a 'DNA walk'. We then use the mapping to provide a quantitative measure of the correlation between nucleotides over long distances along the DNA chain. Thus we uncover in the… CONTINUE READING
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