# Long-range correlations in nucleotide sequences

@article{Peng1992LongrangeCI,
title={Long-range correlations in nucleotide sequences},
author={C. Peng and S. Buldyrev and A. Goldberger and S. Havlin and F. Sciortino and M. Simons and H. Stanley},
journal={Nature},
year={1992},
volume={356},
pages={168-170}
}
DNA SEQUENCES have been analysed using models, such as an it-step Markov chain, that incorporate the possibility of short-range nucleotide correlations1. We propose here a method for studying the stochastic properties of nucleotide sequences by constructing a 1:1 map of the nucleotide sequence onto a walk, which we term a 'DNA walk'. We then use the mapping to provide a quantitative measure of the correlation between nucleotides over long distances along the DNA chain. Thus we uncover in the… Expand
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Why genes in pieces?