Long noncoding RNA XIST promotes malignancies of esophageal squamous cell carcinoma via regulation of miR-101/EZH2

@inproceedings{Wu2017LongNR,
  title={Long noncoding RNA XIST promotes malignancies of esophageal squamous cell carcinoma via regulation of miR-101/EZH2},
  author={Xiaoliang Wu and Xiaoxiao Dinglin and Xiaoxia Wang and Wen Luo and Qi Shen and Yong Li and Ling Gu and Qianghua Zhou and Haotu Zhu and Yanjie Li and Chaodi Tan and Xianzi Yang and Zhenfeng Zhang},
  booktitle={Oncotarget},
  year={2017}
}
The long non-coding RNA XIST is a long non-coding RNA that associates with polycomb repressive complex 2 to regulate X-chromosome inactivation in female mammals. The biological roles as well as the underlying mechanisms of XIST in esophageal squamous cell carcinoma remained yet to be solved. Our data indicated that XIST was significantly upregulated in esophageal squamous cancerous tissues and cancer cell lines, as compared with that in the corresponding non-cancerous tissues and immortalized… CONTINUE READING