Long noncoding RNA LINC00165-induced by STAT3 exerts oncogenic properties via interaction with Polycomb Repressive Complex 2 to promote EMT in gastric cancer.
@article{Jin2018LongNR, title={Long noncoding RNA LINC00165-induced by STAT3 exerts oncogenic properties via interaction with Polycomb Repressive Complex 2 to promote EMT in gastric cancer.}, author={Y. Jin and P. Wu and Wenjing Zhao and X. Wang and J. Yang and Xinying Huo and J. Chen and W. De and F. Yang}, journal={Biochemical and biophysical research communications}, year={2018}, volume={507 1-4}, pages={ 223-230 } }
Long non-coding RNAs (lncRNAs) are a crucial member of the non-coding RNA family, and increasing evidence demonstrates that lncRNAs participate in the initiation and progression of cancers. Our study aimed to explore the role of the lncRNA LINC00165 in gastric cancer (GC) development. In the present study, our results showed that LINC00165 was upregulated in GC tissues and cell lines and high expression of LINC00165 was correlated with tumor-node-metastasis stage, invasion depth, and overall… CONTINUE READING
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