Long noncoding RNA H19 contributes to gallbladder cancer cell proliferation by modulated miR-194-5p targeting AKT2

@article{Wang2016LongNR,
  title={Long noncoding RNA H19 contributes to gallbladder cancer cell proliferation by modulated miR-194-5p targeting AKT2},
  author={Shou-Hua Wang and Xiao-Cai Wu and Ming-di Zhang and Ming-zhe Weng and Di Zhou and Zhi-wei Quan},
  journal={Tumor Biology},
  year={2016},
  volume={37},
  pages={9721-9730}
}
Gallbladder cancer (GBC) is a highly malignant cancer with poor prognosis. Although long noncoding RNA (lncRNA) H19 has been reported to play vital role in many human cancers, whether it is involved in GBC proliferation is still unknown. This study was designed to explore the effect of H19 in GBC cell proliferation. The expression of H19 and AKT2 were significantly elevated in GBC tissues, and the level of miR-194-5p is markedly decreased. Moreover, the RNA levels of H19 and AKT2 were… CONTINUE READING
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