Long non-coding RNAs in cancer progression

@article{Tano2012LongNR,
  title={Long non-coding RNAs in cancer progression},
  author={K. Tano and N. Akimitsu},
  journal={Frontiers in Genetics},
  year={2012},
  volume={3}
}
  • K. Tano, N. Akimitsu
  • Published 2012
  • Medicine, Biology
  • Frontiers in Genetics
  • Recent large-scale transcriptome analyses have revealed that transcription is spread throughout the mammalian genomes, yielding large numbers of transcripts, including long non-coding RNAs (lncRNAs) with little or no protein-coding capacity. Dozens of lncRNAs have been identified as biologically significant. In many cases, lncRNAs act as key molecules in the regulation of processes such as chromatin remodeling, transcription, and post-transcriptional processing. Several lncRNAs (e.g., MALAT1… CONTINUE READING

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