Long non-coding RNA expression profiles predict clinical phenotypes in glioma.

@article{Zhang2012LongNR,
  title={Long non-coding RNA expression profiles predict clinical phenotypes in glioma.},
  author={Xiaoqin Zhang and Stella Sun and Jenny Kan Suen Pu and Anderson Chun On Tsang and D. W. K. Lee and Venus On Ying Man and Wai Man Lui and Stanley Thian Sze Wong and Gilberto Ka-Kit Leung},
  journal={Neurobiology of disease},
  year={2012},
  volume={48 1},
  pages={1-8}
}
Glioma is the commonest form of primary brain tumor in adults with varying malignancy grades and histological subtypes. Long non-coding RNAs (lncRNAs) are a novel class of non-protein-coding transcripts that have been shown to play important roles in cancer development. To discover novel tumor-related lncRNAs and determine their associations with glioma subtypes, we first applied a lncRNA classification pipeline to identify 1970 lncRNAs that were represented on Affymetrix HG-U133 Plus 2.0 array… CONTINUE READING