Long non-coding RNA exchange during the oocyte-to-embryo transition in mice

@inproceedings{Karlic2017LongNR,
  title={Long non-coding RNA exchange during the oocyte-to-embryo transition in mice},
  author={Rosa Karlic and Sravya Ganesh and Vedran Franke and Eli{\vs}ka Svobodov{\'a} and Jana Urbanov{\'a} and Yutaka Suzuki and Fugaku Aoki and Kristian Vlahovicek and Petr Svoboda},
  booktitle={DNA research : an international journal for rapid publication of reports on genes and genomes},
  year={2017}
}
The oocyte-to-embryo transition (OET) transforms a differentiated gamete into pluripotent blastomeres. The accompanying maternal-zygotic RNA exchange involves remodeling of the long non-coding RNA (lncRNA) pool. Here, we used next generation sequencing and de novo transcript assembly to define the core population of 1,600 lncRNAs expressed during the OET… CONTINUE READING